Key result
Wastewater EVD68 RNA concentrations in two California communities positively correlated with statewide laboratory-confirmed EVD68 cases (Kendall's tau=0.47 and 0.50, p<0.001).
Observational
Yes
Wastewater surveillance for enterovirus D68 accurately reflects statewide clinical case trends, providing a potential early warning system for outbreaks.
This is the authors' abstract. We don't add key points for this paper.
In this retrospective study, enterovirus D68 (EVD68) genomic RNA in wastewater solids was measured longitudinally at two California wastewater treatment plants twice per week for 26 months. EVD68 RNA was undetectable except when concentrations increased between mid-July and mid-December 2022, during which time EVD68 cases were confirmed in the state.
Wastewater EVD68 detection matched confirmed cases; supports surveillance research but leaves clinical utility open.
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Boehm et al. (2023) conducted an observational in Enterovirus D68. Wastewater surveillance for EVD68 RNA vs. Statewide laboratory-confirmed EVD68 cases was evaluated on Correlation between weekly median wastewater EVD68 RNA concentrations and weekly case counts (Kendall's tau=0.47 and 0.50, p=<0.001). Wastewater EVD68 RNA concentrations in two California communities positively correlated with statewide laboratory-confirmed EVD68 cases (Kendall's tau=0.47 and 0.50, p<0.001).
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