Key result
Enterovirus D68 RNA surges in wastewater coincide with peaks in confirmed clinical cases.
Wastewater surveillance of EV-D68 RNA correlates with clinical case peaks, demonstrating its utility for tracking outbreaks.
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May complement clinical surveillance for EV-D68; extends observational evidence for wastewater-based viral monitoring.
In this retrospective study, we measured enterovirus D68 (EV-D68) genomic RNA in wastewater solids longitudinally at 2 California, USA, wastewater treatment plants twice per week for 26 months. EV-D68 RNA was undetectable except when concentrations increased from mid-July to mid-December 2022, which coincided with a peak in confirmed EV-D68 cases.
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Boehm et al. (2023) studied this question. Enterovirus D68 RNA concentrations in wastewater solids were undetectable except during a surge from mid-July to mid-December 2022 that coincided with a peak in confirmed cases.
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