What question did this study set out to answer?

To determine whether the Ranson score predicts clinical outcomes in severe acute pancreatitis more accurately than APACHE III, and to evaluate the prognostic value of individual Ranson components.

June 1, 2002Archives of Surgery

Severity Scoring for Prognostication in Patients With Severe Acute Pancreatitis

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Authors

SESoumitra R. EachempatiCornell University LHLynn J. HydoUniversity of New Brunswick PBPhilip S. BarieUniversity of New Brunswick

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Implication

Prospective cohort study shows Ranson scores predict mortality in severe acute pancreatitis, indicating 48-hour variables offer superior prognostic utility.

Key Points

To determine whether the Ranson score predicts clinical outcomes in severe acute pancreatitis more accurately than APACHE III, and to evaluate the prognostic value of individual Ranson components.
Prospectively evaluated N=76 patients (mean age 61.8 ± 1.9 years) admitted with severe acute pancreatitis to a university surgical intensive care unit.
Recorded individual and total Ranson criteria alongside APACHE II and APACHE III scores.
Analyzed predictors of mortality, operative debridement, and ICU stay exceeding 7 days using univariate and multivariate analysis of variance.
Overall mortality was 21.1%, with significantly higher positive Ranson variables in nonsurvivors compared with survivors (5.6 ± 0.5 vs 3.4 ± 0.2; P < .001).
Nonsurvivors demonstrated significantly higher APACHE III scores (76.9 ± 9.9 vs 40.5 ± 2.5; P < .001) and different ICU lengths of stay (24.9 ± 7.5 vs 76.5 ± 1.9 days; P = .002).
Ranson variables assessed at 48 hours—specifically blood urea nitrogen, calcium, base deficit, and fluid sequestration—independently predicted mortality more accurately than admission variables.

Cite This Study

Eachempati et al. (2002) studied this question.

synapsesocial.com/papers/6a9554dec163d75667fa8496 https://doi.org/10.1001/archsurg.137.6.730

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Implication

Prospective cohort study shows Ranson scores predict mortality in severe acute pancreatitis, indicating 48-hour variables offer superior prognostic utility.

Severity Scoring for Prognostication in Patients With Severe Acute Pancreatitis

Discussion

Member takes

Implication

Key Points

Cite This Study

Severity Scoring for Prognostication in Patients With Severe Acute Pancreatitis

Discussion

Member takes

Implication

Key Points

Cite This Study

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