Key result
Oral contraceptive use among women aged 20-45 admitted with hypertension was almost twice the expected rate, and blood pressure improved in 9 of 15 women upon stopping the medication.
Why the study?
Does stopping oral contraceptives reduce blood pressure in young women admitted with severe hypertension?
Observational
Does stopping oral contraceptives reduce blood pressure in young women admitted with severe hypertension?
Effect estimate: almost twice that expected
Oral contraceptive use is associated with severe hypertension in young women, and stopping the medication frequently leads to normalization or improvement of blood pressure.
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May support oral contraceptive cessation in young hypertensive women; leaves open causal confirmation in randomized trials.
M. R. Wallace (1971) conducted an observational in Severe hypertension. Oral contraceptives vs. General population / stopping medication was evaluated on Incidence of oral contraceptive use and blood pressure response to stopping (almost twice that expected). Oral contraceptive use among women aged 20-45 admitted with hypertension was almost twice the expected rate, and blood pressure improved in 9 of 15 women upon stopping the medication.
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