Ultrastructure of the Peripheral Nervous System and Sense Organs.

This is an extraordinarily handsome volume filled with electron micrographs of the highest quality, each with a succinct explanatory paragraph. A useful but somewhat old bibliography completes the book. The first third concerns the peripheral nervous system, and has been prepared by Albert Bischoff, neurologist and neuropathologist at the University of Zurich. It begins with a useful section on normal ultrastructure of the nerve, demonstrating axoplasm, myelin, and Schwann cells including the pi and mu granules. It then goes on to illustrate general cytopathologic changes such as axonal degeneration, macrophages, etc. Following is an excellent group of micrographs concerning specific lesions of biopsied peripheral nerve in certain human diseases, emphasizing the leukodystrophies but also including a few others such as diabetic neuropathy and amyloidosis. A very few experimental lesions are shown including tri-orthocresyl phosphate intoxication and ischemia. The motor end plate is considered briefly in the experimental animal. The second