Key result
Admission tachycardia (>100 bpm) was associated with an increased risk of severe adverse cardiac events in patients with STEMI following primary percutaneous coronary intervention.
Why the study?
Heart rate has been correlated with adverse outcomes, but its effect on in-hospital outcomes after primary PCI required investigation.
Does admission tachycardia increase the risk of severe adverse cardiac events in patients with STEMI undergoing primary percutaneous coronary intervention?
Observational (n=63)
No
Does admission tachycardia increase the risk of severe adverse cardiac events in patients with STEMI undergoing primary percutaneous coronary intervention?
Admission tachycardia (>100 bpm) serves as a prognostic indicator for increased risk of severe adverse cardiac events in STEMI patients undergoing primary PCI.
Answers are grounded in this paper and cite their sources.
May support risk stratification by admission heart rate in STEMI post-PPCI; hypothesis-generating and requires prospective validation before guiding care.
Background: Several studies showed that there is high correlation between heart rate and high adverse outcomes rates. Objective: The aim of the current study is to investigate the effect of heart rate on admission in hospital-outcome of patients undergoing primary percutaneous coronary intervention. Patients and methods: Over the course of 7 months, from July 2019 to January 2020, 63 patients were enrolled in a prospective comparative study at the Cardiology Department of Zagazig University Hospitals. Enrolled patients were diagnosed with acute ST-elevation myocardial infarction (STEMI) and then treated with primary percutaneous coronary intervention. Ejection fraction and coronary angioplasty were assessed in all patients. Results: Significant positive correlations were found between age and heart rate above 100 bpm, also between systolic blood pressure and diastolic blood pressure, with significant negative correlations between systolic blood pressure and left ventricular end-diastolic volume (LVEDV), between diastolic blood pressure and LVEDV, and also between ejection fraction and LVEDV and left ventricular end-systolic volume (LVESV). Among group with heart rate above 100 bpm a significant positive correlation between LVEDV and LVESV was found. Conclusion: The presence of admission tachycardia was linked to increased risk of severe adverse cardiac events in patients with STEMI following primary percutaneous coronary intervention, despite the lack of an association between admission bradycardia and serious cardiac outcomes. Further studies with large sample size are recommended to confirm the current results.
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Ammar et al. (2022) conducted an observational in Acute ST-elevation myocardial infarction (STEMI) (n=63). Admission tachycardia (heart rate > 100 bpm) vs. Admission bradycardia or normal heart rate was evaluated on Severe adverse cardiac events / in-hospital outcome. Admission tachycardia (>100 bpm) was associated with an increased risk of severe adverse cardiac events in patients with STEMI following primary percutaneous coronary intervention.
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