Key result
Left ventricular hypertrophy is a powerful predictor of cardiovascular events in the general population and in patients with essential hypertension.
This review highlights left ventricular hypertrophy as a powerful, independent predictor of cardiovascular events in hypertensive patients and emphasizes its reversal as a major therapeutic goal.
Supports LVH evaluation for risk stratification in hypertension; leaves open whether reversal improves hard endpoints in RCTs.
In the general population and in patients with essential hypertension the presence of left ventricular hypertrophy is a powerful predictor of cardiovascular events, independent of blood pressure and other cardiovascular risk factors. The prevalence of left ventricular hypertrophy increases with age and with the severity of renal impairment. Left ventricular hypertrophy is also a sensitive indicator of vascular structural changes in both large and small arteries. The possibility of reversing left ventricular hypertrophy therefore represents a major therapeutic goal for the treatment of hypertensive patients. Several studies examining the characteristics of left ventricular hypertrophy in the elderly, the interrelations between cardiac and vascular hypertrophy, the possibility of reversing left ventricular hypertrophy and its consequent prognostic value will be reported and commented on in the present review.
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Agabiti‐Rosei et al. (1998) conducted a review in Essential hypertension and left ventricular hypertrophy. Left ventricular hypertrophy was evaluated. Left ventricular hypertrophy is a powerful predictor of cardiovascular events in the general population and in patients with essential hypertension.
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