Key result
Angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers followed by calcium channel antagonists most rapidly facilitate the regression of left ventricular hypertrophy.
Population
Patients with hypertension and left ventricular hypertrophy
Design
Review
Authors
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May inform antihypertensive choice for faster LVH regression; leaves open confirmation in outcome trials.
Regression of hypertensive left ventricular hypertrophy through lifestyle modifications and specific antihypertensive agents (ACEi/ARBs, CCBs) improves diastolic function and reduces cardiovascular risk.
Katholi et al. (2011) conducted a review in Hypertension with left ventricular hypertrophy. Antihypertensive agents, sodium restriction, weight loss was evaluated. Angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers followed by calcium channel antagonists most rapidly facilitate the regression of left ventricular hypertrophy.
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