Key result
A decline in systolic blood pressure was associated with progression to weak hand grip strength at 3 years in elderly outpatients with cardiometabolic diseases (OR 0.928; 95% CI 0.878-0.981; P=0.008).
Why the study?
The study aimed to examine the relationship between changes in clinic blood pressure and frailty and sarcopenia in elderly outpatients with cardiometabolic disease.
Are changes in clinic blood pressure associated with frailty and sarcopenia in elderly outpatients with cardiometabolic diseases?
Cohort (n=691)
Are changes in clinic blood pressure associated with frailty and sarcopenia in elderly outpatients with cardiometabolic diseases?
Odds Ratio: 0.928 (95% CI 0.878–0.981)
p-value: p=0.008
In elderly outpatients with cardiometabolic diseases, a J-curve relationship exists between blood pressure and frailty, with BP declines associated with progression of sarcopenia components.
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BP decline was associated with sarcopenia progression in frail elderly; leaves open whether BP targets warrant adjustment.
Ishikawa et al. (2023) conducted a cohort in Cardiometabolic diseases (n=691). Changes in clinic blood pressure was evaluated on Progression to a weak hand grip strength at 3 years (OR 0.928, 95% CI 0.878-0.981, p=0.008). A decline in systolic blood pressure was associated with progression to weak hand grip strength at 3 years in elderly outpatients with cardiometabolic diseases (OR 0.928; 95% CI 0.878-0.981; P=0.008).
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