Key result
Adverse drug events accounted for 23.3% of medical ICU admissions, of which 59% were preventable and most frequently caused by medication non-compliance.
Population
743 consecutive adult admissions (701 patients) to a medical ICU in a teaching hospital in Paris, France.
Design
Cohort
Follow-up
until hospital discharge
Authors
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ADEs drive nearly one-quarter of medical ICU admissions with 59% preventable; leaves open optimal prevention strategies before practice change.
Observational (n=743)
No
Adverse drug events are a major cause of medical ICU admissions, with over half being preventable, highlighting a significant area for quality improvement and cost reduction.
Jolivot et al. (2016) conducted an observational in ICU admissions (n=743). Adverse drug events vs. Admissions not related to adverse drug events was evaluated on Incidence of ICU admissions due to an adverse drug event (95% CI 20.4-26.5). Adverse drug events accounted for 23.3% of medical ICU admissions, of which 59% were preventable and most frequently caused by medication non-compliance.
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