Key result
Green tea polyphenols reduced fat deposits and ameliorated hypoadiponectinemia in high fat-fed rats, likely mediated via the erk1/2-PPARγ-adiponectin pathway.
Why the study?
Do green tea polyphenols reduce fat deposits and improve adiponectin levels in high fat-fed rats?
Population
30 male Wistar rats fed a high-fat diet, and in vitro visceral adipose tissue cultured in DMEM with high…
Comparison
Green tea polyphenols administered via drinking… vs High-fat diet alone and standard chow control…
Design
Preclinical, randomly divided into 5 groups
Follow-up
26 weeks
Authors
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Does not support clinical use; leaves open whether erk1/2-PPARγ-adiponectin effects translate to human metabolic disease.
Do green tea polyphenols reduce fat deposits and improve adiponectin levels in high fat-fed rats?
p-value: p=<0.05
Green tea polyphenols reduce fat deposits and ameliorate hypoadiponectinemia in high-fat-fed rats, likely mediated via the erk1/2-PPARγ-adiponectin pathway.
Tian et al. (2013) studied Obesity (High fat diet-induced) (n=30). Green tea polyphenols (GTPs) vs. High-fat diet without GTPs was evaluated on Visceral adipose tissue (VAT) accumulation and adiponectin levels (p=<0.05). Green tea polyphenols reduced fat deposits and ameliorated hypoadiponectinemia in high fat-fed rats, likely mediated via the erk1/2-PPARγ-adiponectin pathway.
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