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splitting of the finger-nails provided me with a clue to the diagnosis in these cases.The coexistence of nail changes and a raised serum uric acid in 19 cases would appear to suggest that reeding and splitting and brittle- ness, either individually or together, may be a frequent physical sign in hyperuricaemia and might warrant further investigation-I am, etc.,
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Heffernan et al. (1969) studied this question.
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