Key result
The non-polio acute flaccid paralysis rate in the East and Southern African sub-region significantly increased from 2.7 in 2012 to 3.5 in 2019 per 100,000 children under 15 years (P=0.040).
Why the study?
Sensitive acute flaccid paralysis surveillance is critical for polio eradication, and assessment was needed to document evidence and support the WHO AFRO region certification process.
Population
46,014 reported acute flaccid paralysis cases from 19 ESA countries
Design
Descriptive surveillance performance assessment
Authors
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Ebola disrupted subnational AFP surveillance performance; leaves open whether targeted reinforcements can sustain eradication gains in future crises.
Observational (n=46,014)
Yes
Absolute Event Rate: 3.5% vs 2.7%
p-value: p=0.040
AFP surveillance performance in East and Southern African countries showed a significant increase in sensitivity from 2012 to 2019, supporting polio eradication certification efforts.
Manyanga et al. (2020) conducted an observational in Acute flaccid paralysis (AFP) (n=46,014). Time period (2019) vs. Time period (2012) was evaluated on Non-polio AFP rate per 100,000 population aged less than 15 years (95% CI 0.035-1.564, p=0.040). The non-polio acute flaccid paralysis rate in the East and Southern African sub-region significantly increased from 2.7 in 2012 to 3.5 in 2019 per 100,000 children under 15 years (P=0.040).
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