Key result
Octogenarian ICD recipients experienced similar rates of any device therapy (P=0.78) and time to death or serious illness compared to younger septuagenarians.
Why the study?
Does ICD implantation in octogenarians result in different rates of device therapies or nonarrhythmic death/morbidity compared to septuagenarians?
Cohort (n=199)
Does ICD implantation in octogenarians result in different rates of device therapies or nonarrhythmic death/morbidity compared to septuagenarians?
p-value: p=0.78
Octogenarians have similar rates of arrhythmic episodes and severe comorbidities as septuagenarians after ICD implantation, suggesting age alone should not be a contraindication.
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Supports individualized ICD decisions in octogenarians; leaves open confirmation via randomized trials before broadening indications.
Daniels et al. (2009) conducted a cohort in Implantable cardioverter-defibrillator (ICD) recipients (n=199). Age ≥80 years (octogenarians) vs. Age 70-79 years (septuagenarians) was evaluated on Any device therapy per patient-year (p=0.78). Octogenarian ICD recipients experienced similar rates of any device therapy (P=0.78) and time to death or serious illness compared to younger septuagenarians.
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