Key result
In patients with implantable cardioverter-defibrillators, advancing age was independently associated with an increased risk of all-cause death (HR 1.04) but not with adverse cardiovascular events.
Why the study?
It was unclear whether implantable cardioverter-defibrillators are equally effective across all age groups.
Observational (n=416)
Yes
Hazard Ratio: 1.04 (95% CI 1.01–1.06)
p-value: p=0.004
Age is independently associated with all-cause death but not with adverse cardiovascular events or appropriate ICD therapy, suggesting that elderly patients still derive arrhythmic benefit from ICD implantation.
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Age may modify long-term ICD outcomes; leaves open whether effectiveness differs across age groups in clinical practice.
Hagiwara et al. (2024) conducted an observational in Implantable cardioverter-defibrillator (ICD) indication (n=416). Advancing age vs. Younger age was evaluated on All-cause death (HR 1.04, 95% CI 1.01-1.06, p=0.004). In patients with implantable cardioverter-defibrillators, advancing age was independently associated with an increased risk of all-cause death (HR 1.04) but not with adverse cardiovascular events.
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