Key result
Perioperative use of intravenous magnesium sulfate decreases postoperative pain compared to placebo, potentially leading to decreased opioid utilization.
Why the study?
Anesthesia providers use non-opioid medications to reduce opioid use, motivating the condensation of evidence on intravenous magnesium sulfate to guide safe utilization for reducing postoperative pain.
Does intravenous magnesium sulfate decrease postoperative pain compared to placebo?
Does intravenous magnesium sulfate decrease postoperative pain compared to placebo?
Intravenous magnesium sulfate is an effective non-opioid adjunct for decreasing postoperative pain and potentially reducing opioid use.
Adjunctive IV magnesium may lower pain and opioid needs in orthopedic surgery; extends prior RCTs with new Level 2 data.
Anesthesia providers currently use non-opioid medications in the effort to decrease opioid use.In a randomized controlled trial in 1996, it was first discovered that magnesium sulfate decreased postoperative pain.Further studies from 2013 until 2018 compared intravenous magnesium sulfate versus placebo to decrease postoperative pain.These included five systematic reviews, seven randomized controlled trials (RCTs), and one review article which included 5,858 patients.The data gained from these articles was condensed into information for anesthesia providers so they would be able to safely utilize magnesium sulfate to decrease postoperative pain, which could lead to decreased opioid utilization.
No takes yet. Share an insight, caveat, or question.
Tracy Beckham (2020) conducted a review in Postoperative pain (n=5,858). Intravenous magnesium sulfate vs. Placebo was evaluated on Postoperative pain. Perioperative use of intravenous magnesium sulfate decreases postoperative pain compared to placebo, potentially leading to decreased opioid utilization.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: