Anesthesia providers currently use non-opioid medications in the effort to decrease opioid use.In a randomized controlled trial in 1996, it was first discovered that magnesium sulfate decreased postoperative pain.Further studies from 2013 until 2018 compared intravenous magnesium sulfate versus placebo to decrease postoperative pain.These included five systematic reviews, seven randomized controlled trials (RCTs), and one review article which included 5,858 patients.The data gained from these articles was condensed into information for anesthesia providers so they would be able to safely utilize magnesium sulfate to decrease postoperative pain, which could lead to decreased opioid utilization.
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Tracy Beckham (2020) studied this question.
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