Key result
In young adults under 30 years with acute coronary syndrome, the 5-year major adverse cardiac event rate was 19% overall, with no significant difference between those with atypical etiologies and those with atherosclerosis (10% vs 24%, p=0.62).
Population
27 patients with acute coronary syndrome aged <30 years, mean age 26.8 ± 3.5 years, 81% men, referred to two…
Design
Cohort
Follow-up
5 years
Authors
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Should not yet alter etiology-based management in young ACS; leaves open dedicated prevention trials.
Cohort (n=27)
Yes
Absolute Event Rate: 10% vs 24%
p-value: p=0.62
ACS in patients under 30 is rare (0.05% of angiograms) and has diverse etiologies, but shows satisfactory 5-year clinical outcomes with a 19% MACE rate.
Puricel et al. (2013) conducted a cohort in Acute coronary syndrome (n=27). Atypical etiology (non-atherosclerosis) vs. Atherosclerosis was evaluated on Major adverse cardiac event (MACE) at 5 years (p=0.62). In young adults under 30 years with acute coronary syndrome, the 5-year major adverse cardiac event rate was 19% overall, with no significant difference between those with atypical etiologies and those with atherosclerosis (10% vs 24%, p=0.62).
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