Key result
Specific anatomic features, such as lesion angulation (RR 1.92; 95% CI 1.9-3.07) and proximal location, significantly increased the risk of plaque rupture and acute coronary syndromes.
Observational (n=183)
Relative Risk: 1.92 (95% CI 1.9–3.07)
Specific anatomic features, such as proximal location, angulation, and proximity to bifurcations, strongly predispose coronary plaques to rupture and cause acute coronary syndromes.
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Anatomic features may identify higher-risk plaques for closer monitoring; leaves open whether targeting them improves outcomes in prospective studies.
Katritsis et al. (2008) conducted an observational in Acute Coronary Syndromes (n=183). Lesion angulation vs. Absence of lesion angulation was evaluated on Acute coronary syndrome (plaque rupture) in the left anterior descending artery (RR 1.92, 95% CI 1.9-3.07). Specific anatomic features, such as lesion angulation (RR 1.92; 95% CI 1.9-3.07) and proximal location, significantly increased the risk of plaque rupture and acute coronary syndromes.
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