Key result
A hypertensive response to exercise was associated with a higher aortic stiffness index and lower aortic distensibility compared to a normotensive response.
Why the study?
Are aortic elastic properties impaired in patients with a hypertensive response to exercise testing compared to normotensive responders?
Observational (n=66)
Are aortic elastic properties impaired in patients with a hypertensive response to exercise testing compared to normotensive responders?
Patients with a hypertensive response to exercise testing exhibit deteriorated arterial elastic properties, suggesting early vascular changes.
Answers are grounded in this paper and cite their sources.
May signal early vascular changes in exercise hypertension; leaves open prognostic value and need for longitudinal studies.
We aimed to evaluate the aortic elastic properties in subjects with hypertensive response to exercise stress test (HRE). Sixty-six patients were divided into two groups (33 patients in HRE group and 33 patients in normotensive group). Baseline demographic characteristics were similar. The mean aortic stiffness index (ASI) was significantly higher (p=0.001) whereas aortic distensibility (AD) was significantly lower (p=0.029) in patients suggesting HRE. The C-reactive protein levels of patients with HRE was higher in the HRE group (p=0.03). AD was significantly correlated with age (r=-0.406, p<0.001), pre-test systolic blood presure (SBP) (r=-0.427, p<0.001), peak exercise SBP (r=-0.307, p=0.01), peak exercise diastolic blood presure (DBP) (r=-0.315, p=0.008), and recovery time (3 min) SBP (r=-0.497, p=0.004). Age (β=-0.506, p=0.003) and peak DBP (β=-0.322, p=0.049) were independent predictors of decreased AD. In conclusion, we found a deterioration in arterial elastic properties in patients with HRE.
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Kılıçaslan et al. (2014) conducted an observational in Hypertensive response to exercise stress test (n=66). Hypertensive response to exercise stress test (HRE) vs. Normotensive response was evaluated on Aortic stiffness index (ASI) and aortic distensibility (AD) (p=0.001). A hypertensive response to exercise was associated with a higher aortic stiffness index and lower aortic distensibility compared to a normotensive response.
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