Why the study?
Does prolonged unfractioned heparin prophylaxis reduce delayed deep vein thrombosis in patients undergoing elective total hip replacement?
Does prolonged unfractioned heparin prophylaxis reduce delayed deep vein thrombosis in patients undergoing elective total hip replacement?
Prolonged prophylaxis with unfractioned heparin up to 30 days postoperatively may reduce the risk of delayed proximal DVT compared to 15 days of prophylaxis in patients undergoing total hip replacement.
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Nonsignificant trend favors prolonged UH for proximal DVT prevention after hip replacement; leaves open efficacy pending larger trials.
Manganelli et al. (1998) studied this question.
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