Population
In vitro model using profilin purified from human platelets, G-actin from rabbit skeletal muscle, and…
Comparison
Addition of purified serum Gc vs Profilin-G-actin complex without Gc
Design
Preclinical
Authors
Loading...
Localizes Gc-profilin competition on G-actin; leaves open relevance to cytoskeletal function or vitamin D effects in vivo.
The study demonstrates that vitamin D binding protein (Gc) competes with profilin for binding to G-actin, forming a more stable complex, and maps the binding domain to a specific C-terminal fragment.
Goldschmidt‐Clermont et al. (1986) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: