Prognostic Utility of Advanced Lung Cancer Inflammation Index in Heart Failure with Preserved Ejection Fraction

Figure 1. Patient flow chart.

Figure 2. Distribution of advanced lung cancer inflammation index (ALI). The distribution of ALI is shown in a histogram. The x axis shows ALI level at hospital discharge, and the y axis indicates the number of patients. ALB, albumin; BMI, body mass index; Lymp, lymphocyte; Neu, neutrophil.

Figure 3. Kaplan–Meier curves demonstrating all‐cause mortality stratified by advanced lung cancer inflammation index (ALI) quartile. The Kaplan–Meier analysis for all‐cause mortality in four groups divided by ALI quartile.

Figure 4. Comparison of receiver operating characteristic curves for primary endpoint within 1 year. The areas under the curve (AUCs) of advanced lung cancer inflammation index (ALI), MAGGIC risk score, geriatric nutritional risk index (GNRI) and C‐reactive protein (CRP) were compared. CI, confidence interval.

Figure 5. Incremental value of advanced lung cancer inflammation index (ALI) over the MAGGIC risk score, geriatric nutritional risk index (GNRI) and C‐reactive protein (CRP). The receiver operating characteristic curves of the MAGGIC model (A), GNRI model (B) and CRP model (C) with and without the addition of ALI were compared to evaluate the incremental value of ALI. The MAGGIC model included the MAGGIC risk score, the GNRI model included GNRI, and the CRP model included CRP. Numerically higher areas under the curve (AUCs) for the addition of ALI to each model were found. IDI, integrated discrimination improvement; NRI, net reclassification improvement.

Figure 6. Kaplan–Meier curves demonstrating all‐cause mortality stratified by median advanced lung cancer inflammation index (ALI), MAGGIC risk score, geriatric nutritional risk index (GNRI) and C‐reactive protein (CRP) value. The Kaplan–Meier analyses for all‐cause mortality in four groups divided by median value of ALI and MAGGIC (A), ALI and GNRI (B), and ALI and CRP (C).