Key result
Transcatheter aortic valve implantation resulted in significantly greater improvements in physical task difficulty, emotional task difficulty, and mental health scores at 3 months compared to surgical aortic valve replacement.
Why the study?
Does transcatheter aortic valve implantation improve quality of life compared to surgical aortic valve replacement in patients >70 years of age with severe aortic stenosis?
Cohort (n=79)
No
Does transcatheter aortic valve implantation improve quality of life compared to surgical aortic valve replacement in patients >70 years of age with severe aortic stenosis?
Absolute Event Rate: 13.2% vs 5.1%
p-value: p=0.001
TAVI is associated with significantly greater early improvements in specific quality of life domains compared to SAVR at 3 months in patients over 70 with severe aortic stenosis.
TAVI was associated with greater early QoL gains than SAVR in patients >70; hypothesis-generating and requires RCT confirmation before practice change.
OBJECTIVE: Transcatheter aortic valve implantation has recently been used in the treatment of severe aortic valve stenosis, particularly in patients with high mortality and morbidity rates for open surgery. The purpose of this study was to compare quality of life in patients over 70 years of age undergoing surgical or transcatheter aortic valve implantation, before the procedure and in the early post-procedural period. METHODS: Seventy-nine patients were included in the study, 38 (48.1%) male and 41 (51.9%) female. Mean age of patients was 74.3±5.2 (70-91) years. The surgical aortic valve replacement group consisted of 51 (64.6%) patients and the transcatheter aortic valve replacement group of 28 (35.4%). Quality of life data before the procedure and at the 3rd month postoperatively in patients aged 70 years and older undergoing surgical or transcatheter aortic valve implantation were assessed using the 36-item Short Form Health Survey form. RESULTS: Positive increases in physical task difficulty (13.2±9.8vs. 5.1±7.3) (P=0.001), emotional task difficulty (14.4±11.9 vs.8.5±6.4) (P=0.035), and mental health (0.4±10.4 vs. 9.6±15.1) (P=0.001; P<0.01) scores in patients undergoing transcatheter aortic valve replacement were significantly higher compared to the surgical aortic valve replacement group. No statistically significant difference was determined between the groups in terms of pain, vitality, social function, physical function or general health scores in the preoperative and postoperative periods. CONCLUSION: The positive increase in quality of life parameters in the transcatheter aortic valve implantation group at the 3rd month postoperatively was significantly higher compared to the surgical aortic valve replacement group.
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Kocaaslan et al. (2015) conducted a cohort in Severe Aortic Stenosis (n=79). Transcatheter aortic valve implantation vs. Surgical aortic valve replacement was evaluated on Change in physical task difficulty score at 3 months (p=0.001). Transcatheter aortic valve implantation resulted in significantly greater improvements in physical task difficulty, emotional task difficulty, and mental health scores at 3 months compared to surgical aortic valve replacement.
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