November 7, 2000Circulation
Quality of Life After Aortic Valve Replacement at the Age of >80 Years
Key result
Aortic valve replacement in patients >80 years old resulted in an 11% operative mortality rate, with 1- and 5-year survival rates of 80% and 55%, and improved functional class.
Why the study?
Does aortic valve replacement improve quality of life and provide acceptable survival in patients >80 years old?
Population
133 patients (62 men, 71 women) aged 80 to 91 years (mean 84+/-3 years) with aortic valve disease
Design
Cohort
Follow-up
Up to 5 years (actuarial survival reported at 1 and 5 years)
Authors
Discussion
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Member takes
Implication
May support AVR in selected octogenarians; leaves open need for RCTs to confirm net benefit.
Study Design
Type
Cohort (n=133)
Structured PICO
Does aortic valve replacement improve quality of life and provide acceptable survival in patients >80 years old?
P
Population
133 patients (62 men, 71 women) aged 80 to 91 years (mean 84+/-3 years) with aortic valve disease
I
Intervention
Aortic valve replacement alone or in combination with another procedure
O
Outcome
Quality of life (SF-36), functional outcome (NYHA class), operative mortality, and late survivalpatient reported
Aortic valve replacement in octogenarians carries acceptable operative risk and yields good long-term survival with excellent functional and quality-of-life improvements.
Cite This Study
Sundt et al. (2000) conducted a cohort in Aortic valve disease (n=133). Aortic valve replacement was evaluated on Operative (30 day) mortality rate. Aortic valve replacement in patients >80 years old resulted in an 11% operative mortality rate, with 1- and 5-year survival rates of 80% and 55%, and improved functional class.