Why the study?
Does amyotrophic lateral sclerosis affect heart rate variability compared to healthy subjects?
Population
29 patients with amyotrophic lateral sclerosis (ALS) and 33 age-matched healthy subjects
Comparison
Autoregressive spectral analysis of heart rate… vs Age-matched healthy subjects
Design
Case-control
Authors
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May signal subclinical autonomic involvement in ALS; leaves open whether HRV changes predict outcomes or warrant intervention.
Does amyotrophic lateral sclerosis affect heart rate variability compared to healthy subjects?
Patients with ALS exhibit decreased heart rate variability and a vagal-sympathetic imbalance, suggesting subclinical autonomic nervous system involvement.
Pisano et al. (1995) studied this question.
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