Key result
Asymptomatic HIV-infected patients had lower peak systolic myocardial velocities at the septal (8.84 vs 9.42 cm/s, P<0.001) and lateral mitral annulus compared to healthy controls.
Why the study?
Does Doppler tissue imaging detect subtle left ventricular systolic dysfunction in asymptomatic HIV-infected patients compared to healthy controls?
Population
45 asymptomatic human immunodeficiency virus-infected patients without any heart-related symptoms and 30…
Comparison
Doppler tissue imaging to assess left… vs Healthy control subjects
Design
Case-control
Authors
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DTI may detect subclinical LV systolic dysfunction in asymptomatic HIV; hypothesis-generating and should not yet change practice.
Observational (n=75)
Does Doppler tissue imaging detect subtle left ventricular systolic dysfunction in asymptomatic HIV-infected patients compared to healthy controls?
Absolute Event Rate: 8.84% vs 9.42%
p-value: p=<0.001
Doppler tissue imaging can detect subtle, otherwise undetectable abnormalities in longitudinal left ventricular contractile function in asymptomatic HIV-infected patients.
Karavidas et al. (2008) conducted an observational in Asymptomatic HIV infection (n=75). HIV infection vs. Healthy control subjects was evaluated on Peak systolic myocardial velocities at the septal mitral annulus (Sms) (p=<0.001). Asymptomatic HIV-infected patients had lower peak systolic myocardial velocities at the septal (8.84 vs 9.42 cm/s, P<0.001) and lateral mitral annulus compared to healthy controls.
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