Key result
The causal relationship between enterovirus infections and type 1 diabetes mellitus remains heavily debated and is particularly understudied in regions such as the Middle East and North Africa.
Why the study?
The causal relationship between enterovirus infections and type 1 diabetes mellitus is debated and remains understudied in regions such as the Middle East and North Africa despite high disease burden.
This review highlights the need for further investigation into the relationship between enterovirus infections and type 1 diabetes mellitus, particularly in understudied regions like the Middle East and North Africa.
Leaves the enterovirus–type 1 diabetes link unresolved for clinicians; extends the call for prospective studies in the Middle East and North Africa.
Enteroviruses (EVs) infect millions of people annually. EV infections can be asymptomatic or symptomatic with conditions ranging from mild illnesses to serious diseases such as dilated cardiomyopathy. A causal relationship between EV infections and type 1 diabetes mellitus (T1DM) has been heavily debated, with some studies suggesting that this relationship is not yet conclusive and requires additional evidence, whereas others strongly argue for this correlation. While this relationship is well investigated in some developed countries like the USA and Finland, it is understudied or neglected in other countries like Russia for many reasons such as the low incidence of T1DM. Although the Middle East and North Africa (MENA) are highly affected by T1DM, the role of EVs in the disease in MENA has not been investigated extensively. Therefore, we aimed to address the relationship between T1DM and EVs in MENA and other regions globally.
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Alhazmi et al. (2020) conducted a review in Type 1 Diabetes Mellitus. Enterovirus infection was evaluated. The causal relationship between enterovirus infections and type 1 diabetes mellitus remains heavily debated and is particularly understudied in regions such as the Middle East and North Africa.
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