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Background: Pemphigus Foliaceus (PF) is a rare autoimmune bullous skin disease characterized by the production of pathogenic auto-antibodies against desmoglein 1 and the predominance of the Th2 profile. The quasi exclusivity of the disease in women in our country seems to be the direct consequence of a hormonal impregnation. This study aims to determine whether the serum levels of Follicle-Stimulating Hormone (FSH), Luteinizing Hormone (LH), Prolactin (PRL) and Estradiol (E2) affect PF patients in the endemic southern and whether a relationship exists between these hormones and IgE /IL-4 levels.
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Amina Toumi (2016) studied this question.
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