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Facial aging involves not only the loss of volume, but also the ptosis of the fat compartments, leading to the emergence of deep folds and generating heterogeneous creases and depressions. Thus, this study aims to evaluate the drug injections of active principles in the subcutaneous tissue to reduce the puffiness in the jowl and nasolabial areas, and also the accumulation of fat in the submental area (“double chin”). Therefore, we describe the use of lipolytic and antioxidant substances to reduce facial fat in four patients who were very satisfied with the result of the treatment. Consequently, we conclude that the drug injections of active principles are a practical method with fast and promising results in the treatment of facial fat.
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