Key result
Expanded polytetrafluoroethylene (ePTFE) sutures were completely covered by a tissue sheath resembling native chordae, whereas polypropylene sutures remained mostly exposed up to 12 months.
Why the study?
Does expanded polytetrafluoroethylene (ePTFE) compared to polypropylene improve tissue coverage and flexibility for chordal reconstruction in a canine model?
Does expanded polytetrafluoroethylene (ePTFE) compared to polypropylene improve tissue coverage and flexibility for chordal reconstruction in a canine model?
ePTFE may be superior to polypropylene as an artificial suture material for chordal reconstruction due to better tissue coverage and flexibility.
ePTFE may integrate better than polypropylene in chordal repair; leaves open translation to human outcomes.
No previous reports have compared the suitability of expanded polytetrafluoroethylene (ePTFE) and polypropylene as artificial suture materials for chordal reconstruction in mitral valve plasty (MVP) in the dog. Twelve normal dogs were subjected to MVP using surfaceinduced deep hypothermia. In the short-term group (1.5-4 months after surgery), all ePTFE sutures were covered by a tissue sheath including the paired suture arms, which gave the appearance of native chordae from 2 months after surgery. In contrast, all polypropylene sutures were not covered by tissue, and appeared the same as the paired polypropylene suture arms at the operation. In the long-term group (12 months after surgery), all ePTFE sutures were covered by a tissue sheath, which appeared the same as that in the short-term group, and had flexibility without increased thickness with time. In contrast, although the polypropylene suture was covered completely by a tissue sheath in 1 dog, all the other polypropylene sutures were exposed except for both ends of the suture. ePTFE may be superior to polypropylene as an artificial suture material for chordal reconstruction in MVP.
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Kanemoto et al. (2017) studied Mitral valve plasty (chordal reconstruction) (n=12). Expanded polytetrafluoroethylene (ePTFE) suture vs. Polypropylene suture was evaluated on Tissue sheath coverage of artificial suture material. Expanded polytetrafluoroethylene (ePTFE) sutures were completely covered by a tissue sheath resembling native chordae, whereas polypropylene sutures remained mostly exposed up to 12 months.
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