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March 1, 2004Pacing and Clinical Electrophysiology

Development of Atrial Fibrillation in Patients with Atrioventricular Block After Atrioventricular Synchronized Pacing

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Why the study?

Does DDD pacing compared to VDD pacing increase the development of atrial fibrillation in patients with symptomatic AV block?

Population

152 patients who received permanent pacemakers due to symptomatic atrioventricular block.

Comparison

DDD cardiac pacing vs VDD cardiac pacing

Design

Cohort

Follow-up

mean 48.9 +/- 22.9 months

Authors

CKChi‐Woon KongThe Royal Melbourne HospitalTTTa‐Chuan TuanElectrophysiologyWYWei‐Hsian YinNational Yang Ming Chiao Tung University

Discussion

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Member takes

Overview

May favor VDD over DDD pacing to lower AF risk in AV block; hypothesis-generating and requires randomized confirmation.

Structured PICO

Does DDD pacing compared to VDD pacing increase the development of atrial fibrillation in patients with symptomatic AV block?

P
Population
152 patients (44 women, 108 men; mean age 73) who received permanent pacemakers due to symptomatic atrioventricular (AV) block.
I
Intervention
DDD cardiac pacing
C
Comparator
VDD cardiac pacing
O
Outcome
Occurrence of atrial fibrillation (AF) documented on free-run or 12-lead ECG, any ECG strips, or persistent AF on 24-hour Holter ECG during follow-uphard clinical

In patients with symptomatic AV block, VDD pacing is associated with a significantly lower incidence of developing atrial fibrillation compared to DDD pacing.

Cite This Study

Kong et al. (2004) studied this question.

synapsesocial.com/papers/6a95ad756f6cd511eea6a589https://doi.org/10.1111/j.1540-8159.2004.00440.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Atrial Sensing and AV Synchrony in Single Lead VDD Pacemakers: A Prospective Comparison to DDD Devices with Bipolar Atrial Leads1999 · 54 citations
  2. 2Dual chamber pacing: how many patients remain in DDD mode over the long term?1995 · 35 citations
  3. 3A Multicenter Evaluation of a Single‐Pass Lead VDD Pacing System1991 · 64 citations
  4. 4Long‐Term Follow‐Up of Patients with Single Lead VDD Stimulation1994 · 20 citations
  5. 5Prevention of the Initiation of Atrial Fibrillation: Mechanism and Efficacy of Different Atrial Pacing Modes2000 · 62 citations