Key result
Prolonged Tp-e interval (OR 1.060) and increased Tp-e/QTc ratio (OR 1.148) were independently associated with an increased risk of ventricular arrhythmic events in patients with hypertrophic cardiomyopathy.
Why the study?
Do prolonged Tp-e interval and increased Tp-e/QTc ratio predict ventricular arrhythmic events in patients with hypertrophic cardiomyopathy?
Observational (n=154)
Single-blind
No
Do prolonged Tp-e interval and increased Tp-e/QTc ratio predict ventricular arrhythmic events in patients with hypertrophic cardiomyopathy?
Odds Ratio: 1.06 (95% CI 1.005–1.117)
p-value: p=0.012
Prolonged Tp-e interval and increased Tp-e/QTc ratio on a standard 12-lead ECG are independent predictors of ventricular arrhythmic events in patients with hypertrophic cardiomyopathy.
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May refine arrhythmic risk stratification in HCM; hypothesis-generating and requires prospective validation.
Mehmet Kadri Akboğa (2017) conducted an observational in Hypertrophic cardiomyopathy (n=154). Tp-e interval and Tp-e/QTc ratio vs. Patients without ventricular arrhythmic events was evaluated on Ventricular arrhythmic events (VAEs) (OR 1.060, 95% CI 1.005-1.117, p=0.012). Prolonged Tp-e interval (OR 1.060) and increased Tp-e/QTc ratio (OR 1.148) were independently associated with an increased risk of ventricular arrhythmic events in patients with hypertrophic cardiomyopathy.
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