Key result
Patients with a first myocardial infarction and normal conventional echocardiograms had significantly reduced peak systolic mitral annular velocities by DTI compared to healthy subjects (8.6 vs 9.7 cm/s, P<0.001).
Why the study?
Does Doppler tissue imaging detect abnormal left ventricular function in patients with a first myocardial infarction who have normal function on conventional echocardiography?
Population
19 previously healthy patients with a first myocardial infarction, normal ejection fraction, and no wall…
Comparison
Doppler tissue imaging to assess longitudinal… vs Healthy subjects and conventional echo-Doppler…
Design
Case-control
Authors
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DTI may detect subclinical LV dysfunction post-MI despite normal conventional echo; hypothesis-generating for prognostic utility.
Case-Control (n=35)
Does Doppler tissue imaging detect abnormal left ventricular function in patients with a first myocardial infarction who have normal function on conventional echocardiography?
Absolute Event Rate: 8.6% vs 9.7%
p-value: p=<0.001
Doppler tissue imaging can detect mild subendocardial damage, evidenced by reduced mitral annular velocities, in patients with a first myocardial infarction who appear to have normal left ventricular function on conventional echocardiography.
Alam et al. (2006) conducted a case-control in First myocardial infarction (n=35). First myocardial infarction vs. Healthy subjects was evaluated on Peak systolic mitral annular velocity (p=<0.001). Patients with a first myocardial infarction and normal conventional echocardiograms had significantly reduced peak systolic mitral annular velocities by DTI compared to healthy subjects (8.6 vs 9.7 cm/s, P<0.001).
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