Key result
Youth with type 2 diabetes had significantly worse arterial stiffness, including higher pulse wave velocity (6.4 vs 5.3 m/s, p<0.01), compared to youth with type 1 diabetes, largely mediated by increased central adiposity and blood pressure.
Why the study?
Do youth with type 2 diabetes have worse arterial stiffness compared to youth with type 1 diabetes?
Cross-Sectional (n=595)
Yes
Do youth with type 2 diabetes have worse arterial stiffness compared to youth with type 1 diabetes?
Absolute Event Rate: 6.4% vs 5.3%
p-value: p=<0.01
Youth with type 2 diabetes exhibit worse arterial stiffness than those with type 1 diabetes, a difference largely mediated by increased central adiposity and higher blood pressure.
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May support earlier vascular risk assessment in youth with type 2 diabetes; leaves open causal mediation and intervention effects.
Wadwa et al. (2010) conducted a cross-sectional in Type 1 and Type 2 Diabetes (n=595). Type 2 diabetes vs. Type 1 diabetes was evaluated on Pulse wave velocity (PWV) (p=<0.01). Youth with type 2 diabetes had significantly worse arterial stiffness, including higher pulse wave velocity (6.4 vs 5.3 m/s, p<0.01), compared to youth with type 1 diabetes, largely mediated by increased central adiposity and blood pressure.
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