Article1 January 1938AN ARTICLE CONTRIBUTED TO AN ANNIVERSARY VOLUME IN HONOR OF DOCTOR JOSEPH HERSEY PRATTTHE URIC ACID IN THE SERUM OF GOUTY AND OF NON-GOUTY INDIVIDUALS: ITS DETERMINATION BY FOLIN'S RECENT METHOD AND ITS SIGNIFICANCE IN THE DIAGNOSIS OF GOUT*BERNARD M. JACOBSON, M.D.BERNARD M. JACOBSON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-11-7-1277 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince the original description by Folin and Denis1in 1913 of a colorimetric method for the estimation of uric acid in blood, and the application of this method in the same year by Pratt2to the study of gout, scores of publications have concerned themselves with both methods and with blood uric acid values in health and disease. To review this vast literature completely would serve no purpose, especially as many divergent results have had as their basis methods of estimation fraught with various sources of error. The present communication describes the use of the most recent Folin method in...Bibliography1. FOLINDENIS OW: A new colorimetric method for the determination of uric acid in blood, Jr. Biol. Chem., 1913, xiii, 469. CrossrefGoogle Scholar2. PRATT J: A study of the uric acid in the blood in gout by the method of Folin and Denis, Trans. Assoc. Am. Phys., 1913, xxviii, 387. Google Scholar3. FOLIN O: Standardized methods for determination of uric acid in unlaked blood and urine, Jr. Biol. Chem., 1933, ci, 111. CrossrefGoogle Scholar4. FOLIN O: Unlaked blood as a basis for blood analysis, Jr. Biol. Chem., 1930, lxxxvi, 173. CrossrefGoogle Scholar5. TALBOTTJACOBSONOBERG JHBMSA: The electrolyte balance in acute gout, Jr. Clin. Invest., 1935, xiv, 411. CrossrefGoogle Scholar6. 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A clinical comparison of 100 cases each of gout, rheumatic fever, and infectious arthritis, Trans. Assoc. Am. Phys., 1928, xliii, 217. Google Scholar28. HENCH PS: The diagnosis of gout and gouty arthritis, Proc. Staff Meetings Mayo Clinic, 1936, xi, 476. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: BERNARD M. JACOBSON, M.D.Affiliations: Boston, Massachusetts*Received for publication August 16, 1937.From the Medical Clinic, Massachusetts General Hospital, and the Department of Medicine, Harvard Medical School, Boston.A considerable part of this work was carried out during a collaborative study of gout by Dr. John H. Talbott of this clinic, and the author. 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ALBERT KEY, M.D., CURRIER MCEWEN, M.D., F.A.C.P.Recent Investigations on Rheumatism and Arthritis in the United StatesThe Diagnosis and Treatment of GoutDiagnosis of Gout. 1 January 1938Volume 11, Issue 7Page: 1277-1295KeywordsBloodGoutHospital medicineUric acid ePublished: 1 December 2008 Issue Published: 1 January 1938 PDF downloadLoading ...
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