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The effect of CO(2) on the spinal cord blood flow was investigated in nine dogs. The flow was closely correlated with the paCO(2) and at about 85 mmHg was double the normocarbic flow. The effect of pO(2) was studied in a further nine dogs. Hypoxia markedly increased the flow which was maximal at paO(2) 30-40 mmHg. The vasoconstrictor effect of hypocarbia was absent or decreased in hypoxia. The response of the cord vessels to the blood gases was very similar to that of the brain.
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I. Griffiths (1973) studied this question.
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