Population
23 patients with Duchenne muscular dystrophy, including 5 with atrophic heart and 18 controls with normal…
Design
Case-control
Follow-up
over 5 years (for definition of atrophic heart)
Authors
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Atrophic heart signals greater impairment in DMD; hypothesis-generating and requires prospective studies before informing care.
DMD patients with atrophic heart exhibit significantly reduced cardiopulmonary function and severe motor disability compared to those with normal left ventricular cavity size.
Matsuoka et al. (1987) studied this question.
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