November 1, 2001Pacing and Clinical Electrophysiology
Cardiac Rhythm Disturbances in Patients with Left Atrial Isomerism
Population
22 patients with left atrial isomerism identified from 1984 to 1998. Age at last follow-up ranged from 2 to…
Design
Cohort
Follow-up
up to 276 months (mean age at last follow-up 90+/-70 months)
Authors
Discussion
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Member takes
Implication
Supports serial ECG surveillance in left atrial isomerism; leaves optimal pacing thresholds and timing open for prospective study.
Structured PICO
P
Population
22 patients with left atrial isomerism (LAI) identified from 1984 to 1998. Age at last follow-up ranged from 2 to 276 months (90+/-70 months). Associated cardiac anomalies included interruption of the inferior vena cava (82%), common atrium (41%), AV canal (64%), double-outlet right ventricle (36%), and pulmonary stenosis (68%).
O
Outcome
Development of bradyarrhythmia (junctional rhythm, sinus bradycardia, and AV block)
Patients with left atrial isomerism have a high probability of developing bradyarrhythmias and varied AV conduction abnormalities over time, independent of open-heart surgery.
Cite This Study
Wu et al. (2001) studied this question.