Why the study?
Does quantitative radionuclide scintigraphy improve early diagnosis and assessment of femoral head involvement in suspected Legg-Calvé-Perthes disease compared to standard radiographs?
Does quantitative radionuclide scintigraphy improve early diagnosis and assessment of femoral head involvement in suspected Legg-Calvé-Perthes disease compared to standard radiographs?
Quantitative radionuclide scintigraphy can reliably diagnose and assess the extent of femoral head involvement in Legg-Calvé-Perthes disease earlier than standard radiographs.
May support earlier LCPD detection than radiographs; hypothesis-generating and requires prospective validation before practice change.
We have developed a method for determining the extent of avascularity of the capital femoral epiphysis in suspected Legg-Calvé-Perthes disease. The avascularity is expressed quantitatively as a percentage of the normal uptake of a radionuclide in the vicinity of the involved hip. In twenty-seven patients who had radionuclide scintigraphy this method was reliable in establishing an early diagnosis of Legg-Calvé-Perthes disease as well as in assessing the amount of involvement of the femoral head. In some patients the diagnosis can be established by radionuclide scintigraphy before the changes of Legg-Calvé-Perthes disease are apparent on standard radiographs.
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LaMont et al. (1981) studied this question.
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