Key result
A polymorphic CACA repeat in the 3' untranslated region of the dystrophin gene was identified with four alleles and demonstrated X-linked co-dominant segregation.
Identified a highly informative CACA repeat polymorphism in the 3' untranslated region of the dystrophin gene, useful for genetic linkage analysis.
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May aid linkage analysis in dystrophinopathies; extends polymorphic markers but leaves clinical utility open pending validation.
Alan H. Beggs, Louis M. Kunkel; A polymorphic CACA repeat in the 3′ untranslated region of dystrophin, Nucleic Acids Research, Volume 18, Issue 7, 11 April
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Beggs et al. (1990) studied this question. CACA repeat polymorphism was evaluated on Allele frequencies. A polymorphic CACA repeat in the 3' untranslated region of the dystrophin gene was identified with four alleles and demonstrated X-linked co-dominant segregation.
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