December 29, 1951BMJOpen Access

L-Noradrenaline as a Vasoconstrictor

View Full Paper

Ask AI

Bookmark

Why the study?

Can urine albumin-to-creatinine ratio (ACR) be accurately estimated from protein-to-creatinine ratio (PCR) to predict kidney failure risk in adults?

Structured PICO

Can urine albumin-to-creatinine ratio (ACR) be accurately estimated from protein-to-creatinine ratio (PCR) to predict kidney failure risk in adults?

Population

47,714 adults in Alberta, Canada, with simultaneous assessments of urine albumin-to-creatinine ratio (ACR) and protein-to-creatinine ratio (PCR), including a subcohort with eGFR<60 ml/min per 1.73 m2

Intervention

Equations to estimate median ACR from PCR using linear splines

Comparator

Measured ACR

Outcome

Accuracy of estimated ACR vs measured ACR in predicting kidney failure risksurrogate

Equations developed to estimate ACR from PCR provide similar kidney failure risk predictions as measured ACR, which is useful for retrospective clinical or research applications.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Supports retrospective kidney failure risk estimation with PCR-derived ACR; leaves open prospective validation before clinical substitution.

Cite This Study

H. C. Churchill‐Davidson (1951) studied this question.

synapsesocial.com/papers/6a95c40bb0131a50eabaee34 https://doi.org/10.1136/bmj.2.4747.1551

View Full Paper

Ask AI

Bookmark

Implication

Supports retrospective kidney failure risk estimation with PCR-derived ACR; leaves open prospective validation before clinical substitution.

L-Noradrenaline as a Vasoconstrictor

Structured PICO

Discussion

Implication

Cite This Study

L-Noradrenaline as a Vasoconstrictor

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider