Key result
Sevoflurane resulted in shorter EEG seizure durations (-23 seconds) and longer times to ECT administration (6.2 vs 3.8 minutes) compared to methohexital.
Why the study?
Does sevoflurane compared to methohexital affect seizure duration and recovery times in patients undergoing electroconvulsive therapy?
Population
12 subjects undergoing electroconvulsive therapy (ECT)
Comparison
Sevoflurane for anesthetic induction vs Methohexital for anesthetic induction
Design
Other
Authors
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Sevoflurane may shorten seizures and delay ECT start; leaves open optimal agent selection in randomized trials.
RCT (n=12)
Does sevoflurane compared to methohexital affect seizure duration and recovery times in patients undergoing electroconvulsive therapy?
Absolute Event Rate: 6.2% vs 3.8%
Sevoflurane is a suitable alternative to methohexital for ECT induction, though it is associated with slightly shorter seizure durations and longer recovery times.
Calarge et al. (2003) conducted an RCT in Electroconvulsive therapy (n=12). Sevoflurane vs. Methohexital was evaluated on Time to administering ECT (minutes). Sevoflurane resulted in shorter EEG seizure durations (-23 seconds) and longer times to ECT administration (6.2 vs 3.8 minutes) compared to methohexital.
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