Why the study?
Does induced hypothyroidism cause deafness and inner ear abnormalities in mice offspring, and can it be prevented by thyroxine?
Does induced hypothyroidism cause deafness and inner ear abnormalities in mice offspring, and can it be prevented by thyroxine?
The study suggests that in Pendred's syndrome, loss of hearing is secondary to hypothyroidism during fetal life and may be mitigated by thyroxine treatment during development.
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Supports fetal hypothyroidism hypothesis for deafness in Pendred syndrome; leaves open thyroxine prevention in humans.
M. S. Deol (1973) studied this question.
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