Key result
MitraClip device migration into the left atrium occurred shortly after placement, resulting in acute severe mitral regurgitation, emergency open heart surgery, and subsequent death.
Why the study?
Despite the safe profile of transcatheter mitral valve repair with MitraClip, complications like device detachment or migration into the left atrium can occur and pose a significant risk.
Case Report (n=1)
Highlights a rare but significant acute complication of MitraClip migration into the left atrium following transcatheter mitral valve repair.
Alerts to rare early MitraClip migration risk despite experienced centers; leaves open need for enhanced monitoring protocols and larger safety registries.
Transcatheter mitral valve repair with the MitraClip device has become an established therapeutic option for the treatment of symptomatic patients with mitral regurgitation and prohibitive surgical risk. Despite its safe profile when performed in experienced centers, complications such as MitraClip device detachment or migration into the left atrium can occur and pose a significant risk. We report a MitraClip device migration into the left atrium short after its placement in a patient with symptomatic mitral valve regurgitation and a history of previous coronary artery bypass grafting and aortic valve replacement.
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Sarridou et al. (2025) conducted a case report in Severe symptomatic mitral regurgitation (n=1). MitraClip was evaluated. MitraClip device migration into the left atrium occurred shortly after placement, resulting in acute severe mitral regurgitation, emergency open heart surgery, and subsequent death.
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