Key result
Histopathological evaluation of a single human patient after catheter-based renal denervation revealed incomplete destruction of the perivascular nerves of the renal arteries.
Population
1 human patient who underwent catheter-based renal denervation
Design
Case_report
Authors
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Incomplete nerve destruction in one case cautions against assuming uniform ablation success; leaves open the need for optimized techniques and larger studies.
Case Report (n=1)
First-in-human histopathological evaluation demonstrates limited destruction of renal nerves following catheter-based renal denervation, providing a plausible explanation for the variable clinical efficacy of the procedure.
Vink et al. (2014) conducted a case report in Resistant hypertension (n=1). Catheter-based renal denervation (RDN) was evaluated on Histopathological evaluation of the effects of RDN on perivascular nerves of the renal arteries. Histopathological evaluation of a single human patient after catheter-based renal denervation revealed incomplete destruction of the perivascular nerves of the renal arteries.
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