Key result
Takotsubo Syndrome was significantly associated with a higher lifetime prevalence of any mood disorder (OR 6.55) and recent antidepressant use, but not with anxiety disorders.
Why the study?
Is Takotsubo Syndrome associated with mood disorders, anxiety disorders, or antidepressant use?
Population
95 subjects, mean age 63.26, predominantly female, from Italy.
Design
Case-control
Authors
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Supports mood disorder assessment in Takotsubo; leaves open whether antidepressants are causal or risk markers.
Case-Control (n=95)
No
Is Takotsubo Syndrome associated with mood disorders, anxiety disorders, or antidepressant use?
Odds Ratio: 6.55 (95% CI 1.47–30.09)
Absolute Event Rate: 31.5% vs 6.58%
p-value: p=0.002
Takotsubo Syndrome is significantly associated with major depressive disorders and the use of antidepressants, but not with anxiety disorders.
Sancassiani et al. (2018) conducted a case-control in Takotsubo Syndrome (n=95). Takotsubo Syndrome vs. Matched controls without Takotsubo Syndrome was evaluated on Lifetime prevalence of any mood disorder (OR 6.55, 95% CI 1.47-30.09, p=0.002). Takotsubo Syndrome was significantly associated with a higher lifetime prevalence of any mood disorder (OR 6.55) and recent antidepressant use, but not with anxiety disorders.
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