Models for diabetic wound healing and healing into percutaneous devices

Delayed healing of chronic ulcers in patients with diabetes and infections resulting from percutaneous medical devices (e.g., vascular access catheters) not only plays a major role in morbidity and mortality, but is a major burden to our healthcare system. In this paper, we review models to study diabetic wound healing and the wound-healing response associated with implanted percutaneous implants.