In lactating goats, VLDL and IDL apoproteins incorporate labeled lysine faster than LDL and HDL.
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Does not support changes in human lipid management; leaves open species-specific apoprotein kinetics in lactation.
Lipoproteins of goat serum were labeled in vivo by intravenous injection of tritium labeled DL-lysine monohydrochloride. The specific radioactivity of the very low density plus intermediate density fractions reached a maximum at 1.2 h, declined sharply until about 9 h, and then more slowly. The specific radioactivities of the low density and high density lipoproteins reached lower maxima at 6.5 h and 8.5 h, respectively.
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Stead et al. (1978) studied this question.
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