Why the study?
Does prior immunization reduce virus yield in tracheal organ cultures from birds inoculated with avian infectious bronchitis virus?
Population
Tracheal organ culture from birds (chickens)
Comparison
Prior immunization against avian infectious… vs Tracheal rings from susceptible birds
Design
Preclinical
Follow-up
up to 96 hours
Authors
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Hypothesis-generating for local tracheal immunity in birds; leaves open translation to in vivo or clinical settings.
Does prior immunization reduce virus yield in tracheal organ cultures from birds inoculated with avian infectious bronchitis virus?
Prior immunization against avian infectious bronchitis virus confers local resistance in tracheal organ cultures, mediated by locally produced immunoglobulins.
Gómez et al. (1974) studied this question.
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